When you are not wearing or cleaning your lashes, keep them in their protective case. I do not recommend base to tip mascara application. Only apply your mascara at the base on your natural lash. Applying to your false lash will affect the integrity and you will not get as many uses out of them.
Lay your lashes flat on a paper towel. Using a q-tip with a bit of warm water, gently roll it over the band of your lashes. Avoid soaking them in water. Doing so can damage the shape and curl. Using tweezers, GENTLY remove any glue remaining on your falsies.